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Edged tool for radiotherapy wipes out huge tumor in the brain. With bold decision of MDT of Hunan Cancer Hospital, it achieves effective achievements in comprehensive treatment

39Admin2018-09-19from:Hunan Cancer Hospital

As is known to all, people have limited capacity in their brains due to protection of staunch skull. If a ‘huge tumor’ with the size of a tennis ball squeezes into the brain, it would be creepy. But such a nightmare befell Ms. Li, a 29-year-old young mother. 

This year, after Ms. Li gave birth to a baby and was still in the lactation period, she came over to the Neurosurgery Department of Hunan Cancer Hospital for she suffered pain and emesis for over half a year. During diagnosis, she showed symptoms of vague vision and evident intracranial hypertension. 

From the MRI in the brain, it could be seen that Ms. Li had a lesion with the size of a fist (7.0 x 5.5cm) that would implicate the ventriculus tertius, the hypothalamus, the optic tract and around 10 critical parts. It was like a timebomb that would explode in the brain at any time. Judged from the symptoms and relevant inspection results, it is clinically diagnosed as being NGGCTs. 

Bearing tormenting intracranial hypertension, Ms. Li often shed tears and felt depressed. But she craved to survive on seeing her baby. She and her family wished that Hunan Cancer Hospital would give her hope of life. 

But it would be too risky to do CSF puncture due to high brain pressure in Ms. Li. Craniotomy would lead to extensive extent of lesion. It can’t be entirely severed. The patient might suffer serious dysneuria or coma. So doctors in the neurosurgery department decided to organize multidisciplinary diagnosis. 

NGGCTs is a rare disease. Theoretically, it has high sensitivity towards radiotherapy, but Ms. Li has a big size of tumor in the brain that would encroach on many parts. According to analysis, she might suffer over 30% ratio on central nervous system transfer. On condition that pathology couldn’t be effectively acquired, the MDT team, patients and family members conducted ample communications. Team of No.2 Department of Radiotherapy on Head and Neck joined Professor Qiu Xiaoguang from Tiantan Hospital affiliated to Capital Medical University in customizing an individualized plan on radiotherapy by starting from diagnosis radiotherapy of 6Gy/3-time dosage. After review in one week, they would go for whole central radiation (whole brain, whole spinal cord) if the tumor shrinks evidently. Then they would continue to conduct whole-body chemotherapy and make regular appraisal by amplifying radiotherapy pertinent to part of the brain.  

According to Han Yaqian, Deputy Director of No.2 Department of Radiotherapy on Head and Neck, dosage of diagnosis radiotherapy of 6Gy is small that only targets at nidus of patient and would barely cause damage to normal tissues of the patient. After diagnostic radiotherapy, the patient showed relieved symptoms of headache, emesis and blurred vision. In magnetic resonance review, her brain tumor shrank by 80% and AFP, the tumor marker, also declined evidently. 

Han Yaqian indicated that TOMO HD spiral fault radiotherapy accelerator, the most advanced in the field so far, in Hunan Cancer Hospital, had unique advantages on particular intractable diseases on the central nervous system. With active help from TOMO Therapy team of Comprehensive Department of Radiotherapy, combination of radiotherapy planning and several plans were launched soon and put into practice. Ms. Li finished the radiotherapy, checked out of the hospital and got recovered soon. She barely suffered any discomfort and her tumor in the brain almost vanished. Her AFP was back to normal. 

Ms. Li will continue to receive professional treatment from professional team of medical oncology on head and neck and receive professional appraisal from teams of the neurosurgery department. After receiving professional treatment and careful nursing, she and her family expressed gratitude to the teams of Hunan Cancer Hospital. 

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